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How is Medical Cannabis Working in Practice?

Franjo Grotenhermen

Lumino are honoured to sponsor The Cannabis Conversation podcast, hosted by Anuj Desai. Over the years, we have had wonderful guests who offer a range of invaluable insights from decades of experience within the cannabis industry, from medical cannabis to recreational and beyond. We will be regularly sharing summaries of our favourite episodes to share the golden nuggets of information that each guest has had to offer.

In today’s episode, we had the privilege of speaking with Franjo Grotenhermen, a medical cannabis patient, doctor, and chairperson at the International Association of Cannabinoid Medicines (IACM). Franjo shared his remarkable journey and extensive experience in the medical cannabis space, shedding light on various aspects of cannabis research, usage, and challenges.

A Journey of Discovery and Advocacy

Franjo’s journey into the realm of medical cannabis began unexpectedly over three decades ago when he fell severely ill, prompting him to explore alternative treatment options. In 1993, he stumbled upon the emerging field of cannabis medicine, inspired by the scientific studies demonstrating the therapeutic potential of cannabinoids. Despite initial skepticism, Franjo immersed himself in the study of cannabis and became a passionate advocate for its medical applications.

In 1993, Franjo stumbled upon the emerging field of cannabis medicine, inspired by the scientific studies demonstrating the therapeutic potential of cannabinoids.

Founding the International Association of Cannabinoid Medicines

Driven by a newfound purpose, Franjo co-founded the Association for Cannabis Medicine in Germany in 1997 and later played a pivotal role in establishing the International Association for Cannabinoid Medicines (IACM) in 2000. Through these organisations, Franjo sought to bridge the gap between scientific research and medical practice, advocating for patient access to cannabis-based therapies worldwide.

Navigating the Cannabis Dilemma

Throughout his career, Franjo has encountered what he terms the “cannabis dilemma.” This dilemma revolves around the tension between the widespread accessibility of cannabis as a natural plant and the regulatory challenges posed by its classification as a controlled substance. Governments grapple with balancing patient needs with regulatory frameworks, highlighting the complexities inherent in cannabis legalisation and medical use.

The Complexity of Cannabis Research

Franjo emphasised the multifaceted nature of cannabis research, citing the vast array of cannabinoids, terpenes, and flavonoids present in the plant. Unlike traditional pharmaceuticals focused on single compounds, cannabis offers a diverse spectrum of therapeutic components, making research and clinical trials challenging yet essential for advancing medical understanding.

A female scientist tests samples of medical cannabis in a lab.

Real-World Evidence vs. Clinical Trials

In evaluating the efficacy of cannabis-based treatments, Franjo stressed the importance of both real-world patient experiences and clinical trials. While clinical trials provide valuable scientific evidence, real-world data offer insights into individual patient responses and preferences. Franjo highlighted the need for a balanced approach, acknowledging the limitations and complexities inherent in studying cannabis as a medicine.

Navigating Risks and Benefits

As with any medication, Franjo emphasised the importance of assessing the risk-benefit profile of cannabis-based therapies. He discussed potential interactions with other medications, pharmacodynamic and pharmacokinetic considerations, and contraindications such as allergic reactions and acute schizophrenia. Franjo underscored the importance of personalised medicine and informed decision-making in cannabis treatment.

Looking Ahead

In closing, Franjo shared his optimism for the future of medical cannabis research and patient care. He highlighted the evolving landscape of cannabis-based therapies, including innovations in delivery methods and the growing recognition of cannabis’ potential across various medical conditions. Franjo’s dedication to advancing cannabis medicine serves as a testament to the ongoing pursuit of knowledge and compassionate care in the field.

Franjo's dedication to advancing cannabis medicine serves as a testament to the ongoing pursuit of knowledge and compassionate care in the field.

Conclusion

Franjo Grotenhermen’s insights offer a compelling glimpse into the complex and evolving world of medical cannabis. From his early advocacy efforts to his current role in shaping global cannabis research, Franjo’s journey exemplifies the transformative potential of cannabis as a medicine. As we navigate the intricacies of regulation, research, and patient care, Franjo’s dedication inspires us to embrace a nuanced understanding of cannabis and its role in modern healthcare.

Thank you for joining us on this enlightening journey through the cannabis conversation. Stay tuned for more episodes exploring the diverse facets of the cannabis industry and its impact on our lives.

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*Disclaimer: The views and opinions expressed in The Cannabis Conversation are those of the individuals interviewed and do not necessarily reflect the official policies or positions of Lumino.*

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